| November 1974 | Established Union Sokki Co., Ltd. Developed a Automatic Polarimeter and a Light Scattering Spectrometer, and started selling these products. |
| October 1981 | Changed the company name to Unisoku Co., Ltd. Developed a rapid scanning spectrophotometer using photodiode array, and applied to the stopped-flow reaction analyzer, and the Laser excited nanosecond time resolution photo- reaction analyzer. |
| April 1986 | Developed a Scanning Tunneling Microscope (STM) for use under atmospheric conditions, and started selling it. |
| August 1989 | Developed an Ultra High Vacuum Scanning Tunneling Microscopy System (UHV STM), and started selling it. |
| October 1991 | Developed an Ultra Low Temperature Ultra High Vacuum Scanning Tunneling Microscopy System (Ultra-LT UHV STM), and started selling it. |
| August 1999 | As the new standard UHV-STM systems, USM-1100, USM-1200, USM-1300 series were completed. |
| August 2000 | Lineup of the new optical instruments RSP-1000, TSP-1000 and CSP-1000 Systems were completed. |
| October 2000 | The Atomic Force Microscope (UHV-AFM) was developed and added to the USM series. |
| August 2003 | Concluded an exclusive distributor contract with RHK Technology, Inc. (Michigan, USA)Started the sales of RHK SPM Systems. |
| October 2004 | Concluded a sales contract with Ultrafast Systems LLC.(Ohio, USA) Started the sales of Ultrafast optical instruments. |
| October 2005 | Developed a UHV Ultra Low Temperature SPM system USM-1400 Series, and started selling it. |
| November 2005 | Concluded an exclusive distributor contract with Scientek Corp. (Taiwan). Started the sales of our UHV SPM in Taiwan. |
| July 2008 | Developed a UHV Room Temperature STM System USM-1000, UHV LT SPM System USM-1500, and started selling it. |
| September 2010 | Unisoku Co.,Ltd. joined Tokyo Instruments, Inc Group |
| Sept 2011 | UNISOKU-TII Instruments Co.,LTD(overseas office) estalished in Beijin. |
| Oct 2011 | The capital was increased to ¥50,000,000. |